Precise definitions of disease may change as new diagnostic modalities, newer clinical research and better clinical experience become available. The result of the recent ESC/ACCF/AHA/WHF expert consensus conference to develop a Universal Definition of Myocardial infarction is now available (http://content.onlinejacc.org/cgi/content/full/j.jacc.2007.09.011v1 ). This effort incorporates troponin changes into the definition and clarifies what to call the clinical syndrome of small troponin elevations after PCI or other coronary artery manipulations. If you do not know the difference between myocardial infarction and myocardial necrosis this article is worth reviewing.
David S. Smith, M.D., Ph.D.
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