What is the role of BIS or other brain activity monitor in decreasing the incidence of awareness?
Reviews of cases in which awareness has occurred have identified cases in which, had BIS monitoring been used, the inadequate level of anesthesia might have been recognized (1). However there appear to be cases in which awareness occurred despite BIS monitoring. This is true for the b-aware and b-unaware trials as well as case reports (2, 3, 4).
1) Bergman IJ et al: Awareness during general anesthesia: a review of 81 cases from the anaesthesia incident monitoring study. Anaesthesia 2002;57:549-556
2) Myles PS: Bispectral index monitoring to prevent awareness during anaesthesia: the B Aware randomized controlled trial. Lancet 2004;363:1757-63
3) Finkel KJ et al: Sensitivity of BIS and MAC in the B-Unaware Trial. ASA Annual Meeting, San Francisco A728
4) Mychaskiw G, et al: Explicit intraoperative recall at a bispectral index of 47. Anesth Analg 2001;92:808-9
David S. Smith, M.D., Ph.D.
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