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January 23, 2008

What anesthetic types are suitable for BIS or similar monitoring?

BIS and other similar monitors that use processed EEG parameters to derive an estimate of anesthetic effect site activity appear to be most sensitive to anesthetic drugs that have their major effect via the GABA a receptor.  These monitors do not “see” the effects of drugs that act via NMDA pathways, endorphin pathways or alpha 2 adrenergic pathways.  Thus drugs such as isoflurane, desflurane, sevoflurane, propofol and etomidate lend themselves to BIS or similar monitoring.

David S. Smith, M.D., Ph.D.

Posted at 01:13 PM in Clinical Care |

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  • Blogmaster
    This blog is organized and maintained by David S. Smith, M.D., Ph.D. Associate Professor of Anesthesiology and Critical Care, University of Pennsylvania. His subspeciality is anesthesia for patients undergoing neurosurgery. For the past 6 years he has had responsibilites for patient safety and clinical care quality improvment in a Department of over 65 faculty who provide anesthesia care for about 24,000 patients each year. Correspondance can be sent to upennanesthesiology@gmail.com
  • Mission Statement
    The purpose of this blog is primarily to provide ongoing contact with former residents and faculty of the Department of Anesthesiology and Critical Care at the University of Pennsylvania, Philadelphia, PA, U.S.A. Others may also have an interest in the topics presented. We plan to discuss a variety of issues related to the practice of anesthesiology with an emphasis on patient safety, risk management and medical legal aspects of care.
  • Disclaimer
    The content and observations on this Weblog come mostly from members of the Department of Anesthesiology and Critical Care of the University of Pennsylvania. However this material does not represent the official opinion of that Department, the University of Pennsylvania or any of its other Departments or Divisions. Medicine is a rapidly changing field. We cannot guarantee that any of the material here is correct or up to date.
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